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Friday, 22 May 2020

RESEARCHERS MAY HAVE UNCOVERED THE ACHILLES HEEL OF VIRUSES


Viruses have an exceptional ability to circumvent the body's immune system and cause diseases. The majority of people recover from a viral infection such as influenza, although the current COVID-19 pandemic demonstrates how dangerous viruses are when there is no effective vaccine or treatment.

Professor and virologist Søren Riis Paludan from the Department of Biomedicine at Aarhus University, Denmark, has been leading a research partnership between Aarhus University, the University of Oxford and the University of Gothenburg, which has brought us one step closer to understanding the tactics used by viruses when they attack the immune system.



Søren Riis Paludan heads a laboratory which carries out research into the immune system's ability to fight diseases caused by the herpes virus, influenza viruses and, most recently, SARS-CoV2, more commonly known as coronavirus.

In the new study, which has just been published in the scientific journal Journal of Experimental Medicine, the researchers have investigated how the herpes simplex virus circumvents the immune system in order to cause infections of the brain. This is a rare infection but one which has a high mortality rate among those who are affected.

"In the study, we found that the herpes simplex virus is capable of inhibiting a protein in the cells, known as STING, which is activated when there is a threat. When STING is inhibited, the body's immune system is also inhibited - the virus thereby puts the brakes on the body's brake, which is supposed to prevent us from becoming ill. Other viruses also make use of the same principle," says Søren Riis Paludan.

Søren Riis Paludan points out that though the study focuses on herpesviruses, there are parallels to the coronavirus. Interestingly, the same protein is also inhibited by many different viruses, including the coronavirus.

"This suggests that we have found an Achilles heel in the virus and the way it establishes infections in the body. Our results lead us to hope that if we can prevent viruses from blocking STING, then we can prevent the virus from replicating. That could pave the way for new principles for treatment of herpes, influenza and also the coronavirus," says Søren Riis Paludan.



He hopes that the research results can be used in the development of antiviral drugs and vaccines in the future.

"Previous studies have also shown that the coronavirus inhibits STING in the same way as the herpes virus. This suggests that we have found a common denominator for several types of virus, and that this is probably an important element in the development of treatment," he says.



Bibliography:

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection
Chiranjeevi Bodda,

 Line S. Reinert, Stefanie Fruhwürth, Timmy Richardo, Chenglong Sun, Bao-cun Zhang, Maria Kalamvoki, Anja Pohlmann, Trine H. Mogensen, Petra Bergström, Lotta Agholme, Peter O’Hare, Beate Sodeik, Mads Gyrd-Hansen, Henrik Zetterberg, Søren R. Paludan

Exp Med (2020) 217 (7): e20191422. 

DOI: https://doi.org/10.1084/jem.20191422.

23 comments:





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    1. My names is Cathy i want to testify about the great spell caster called Priest Ade my husband and i have been married for 5 years now we don't have a child and the doctor told us i can't give birth because my womb have been damaged due to wrong drugs prescription this got me so worried and my husband was not happy so he decided to get married to another girl and divorce me i was so sad i told my friend about it she told me about a powerful spell caster she gave me his email address well i never believe in it that much though i just decided to give him a try and he told me it will take 24hrs to get my husband back to me and i will get pregnant i doubted him the 3rd day my husband came back to me and was crying he said he didn't want the divorce anymore 3 weeks after the doctor confirmed that i was pregnant he can also help you contact him at
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    4. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

      This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  


















      HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

      This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  

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  2. How to have your husband back home with your kids again

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  3. My names is Cathy i want to testify about the great spell caster called Priest Ade my husband and i have been married for 5 years now we don't have a child and the doctor told us i can't give birth because my womb have been damaged due to wrong drugs prescription this got me so worried and my husband was not happy so he decided to get married to another girl and divorce me i was so sad i told my friend about it she told me about a powerful spell caster she gave me his email address well i never believe in it that much though i just decided to give him a try and he told me it will take 24hrs to get my husband back to me and i will get pregnant i doubted him the 3rd day my husband came back to me and was crying he said he didn't want the divorce anymore 3 weeks after the doctor confirmed that i was pregnant he can also help you contact him at
    ancientspiritspellcast@yahoo.com or ancientspiritspellcast@gmail.com 
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  4. HELLO EVERYONE I have been suffering from (HERPES) disease for the past 8 months and had constant pain, especially in my knees. During the first month , I had faith in God that I would be healed someday.This disease started to circulate all over my body and I have been taking treatment from my doctor, a few weeks ago I came on search on the internet if I could get any information concerning the prevention of this disease, on my search I saw a testimony of someone who has been healed from (Hepatitis B and Cancer) by this Man DR WONDERS and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to DR WONDERS telling him about my (HERPES Virus) he told me not to worry that I was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later I started experiencing changes all over me as the DR assured me that I have cured, after 2 weeks i went to my doctor to confirmed if I have been finally healed behold it was TRUE, So friends my advice is if you have such sickness or any other like HSV1,2,HPV1,2,3,CANER HIV,COLE SORES,COPD/MND, ETC you can email DR WONDERS on{DR.WONDERSPELLHOME@YAHOO.COM sir I am indeed grateful for the help you can also CALL/WHATSAPP him on this number+2349059484309 ,,.....



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  5. HELLO EVERYONE I have been suffering from (HERPES) disease for the past 8 months and had constant pain, especially in my knees. During the first month , I had faith in God that I would be healed someday.This disease started to circulate all over my body and I have been taking treatment from my doctor, a few weeks ago I came on search on the internet if I could get any information concerning the prevention of this disease, on my search I saw a testimony of someone who has been healed from (Hepatitis B and Cancer) by this Man DR WONDERS and she also gave the email address of this man and advise we should contact him for any sickness that he would be of help, so I wrote to DR WONDERS telling him about my (HERPES Virus) he told me not to worry that I was going to be cured!! hmm i never believed it,, well after all the procedures and remedy given to me by this man few weeks later I started experiencing changes all over me as the DR assured me that I have cured, after 2 weeks i went to my doctor to confirmed if I have been finally healed behold it was TRUE, So friends my advice is if you have such sickness or any other like HSV1,2,HPV1,2,3,CANER HIV,COLE SORES,COPD/MND, ETC you can email DR WONDERS on{DR.WONDERSPELLHOME@YAHOO.COM sir I am indeed grateful for the help you can also CALL/WHATSAPP him on this number+2349059484309 ,,.....

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  7. I want to share this great testimony to the world on how Dr Aliaro cure me from HSV1&2 with his herbs, I was nervous when i first contact him about the cure for HSV but i decided to give him a try because i was desperate to get cured and be free from HSV. Dr Aliaro prepare the cure and send it to me through UPS,which i use it just the way Dr Aiaro instructed me and thank God today am a beneficiary to these cure and i went back to the hospital after 15 days of taking the herbs and i tested HSV1&2 Negative. So i will tell you all who is looking for a cure to his/her HSV1&2 that Dr Aliaro took research before he could finally get the solution to it and a lot of people are benefiting from him right now. He also cure my friend from HPV. Dr Aliaro heals with natural herbs. Please i urge you to contact him now through his email address: draliarohomeofgrace@gmail.com or call and WhatsApp him on +2347038729039. He is capable of curing HIV/AIDS, HERPES, HPV, HSV1&2, CANCER of all kind,DIABETES and so many other infections.

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  8. Heal from Broken Heart” Reunion Love spell from dr.Adoda brought my husband back” contact dr Adoda to help you get your Ex lover back urgently after breakup/divorce.
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  9. Hello viewers, I'm here to shear my testimony on how Dr.Azu cured my herpes virus/hpv with his herbal medicine,,.I do not have much to say but with all my life i will for ever be grateful to him and God Almighty for using Dr.Azu to reach me when i thought it was all over, today i am happy with my life again after the medical doctor have confirmed my HERPES SIMPLEX VIRUS / HPV of 3 years is gone,i have never in my life believed that HERPES SIMPLEX VIRUS could be cured by herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the power of  Dr.Azu that all hope is not lost yet, try and contact him by any means for any kind of disease. Thanks once again Dr.Azu for your marvelous work may God continue to bless you. You can also reach him today via email: dr.azuherbalhome@gmail.com or +2347087313747.     .

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  10. I want to give my testimony about how i get cuer for my Herpes virus by a great spell home DR LUCKY. Since last 3 months I have  being a virus patient. I never think I live long again and am so grateful to him DR LUCKY . who help me cured my virus last 4 weeks. I was in a  great pain bso I told my bast friends; he told me that there is a great spell caster that can cure my Virus. I asked her if she had his  email, she gave me his email, I emailed him he talked to me and he perform  the necessary rituals and he told me that after two weeks I should go to a  test.Which I did, when to a doctor told me that am now a virus negative I  couldn’t believe myself I went to see another doctor to me result was still  the same, I was human on planet earth, so I emailed him again and thanks him for help me to cure my Harper virus.  Please if you having a similar problem please visit him or contact him on Email Him : drluckylgenegbalespellhome@gmail.com on whatsapp: +2349059880331 Regard...

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  11. Greetings to you all, i am here today on this forum giving a life testimony on how Dr.wonder has cured me from HERPES VIRUS, i have been stocked in bondage with this virus for almost 2 years now, i have tried different means to get this sickness out of my body i also heard there was no cure to the virus, all the possible ways i tried did not work out for me, i do have the faith that i was going to be cured one day, as i was a strong believer in God and also in miracles, One day as i was on the internet i came across some amazing testimonies concerning how Dr wonder has cured different people from various sickness with his Herbal Herbs Medicine, they all advised we contact Dr wonder for any problem, with that i had the courage and i contacted Dr Wonder i told him about my Sickness, He told me not to worry that he was going to prepare some Herbal Medicine for me, after some time in communication with Dr.wonder, he finally prepared for me some herbs which he sent to me and he also gave me prescriptions on how to take the herbal medicine , My good friends after taking Dr.wonder Herbs for some weeks i started to experience changes in me and from there, I noticed my HERPES VIRUS was no longer in my body, as i have also gone for test, Today i am fit and healthy to live life again, I am so happy for the good work of Dr.wonder in my life, Friends if you are having any type of disease problem kindly email Dr.wonder on {DR.WONDERSPELLHOME@YAHOO.COM} or call him on +2349059484309 for help  God Bless you Sir

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  12. After being in relationship with my wife for years, she broke up with me. I did everything within my reach to bring her back but all was in vain, I wanted her back so badly because of the love I had for her, I begged her with everything, I made promises but she refused. I explained my problem to my friend and he suggested that I should rather contact a spell caster that could help me cast a spell to bring her back , I had no choice than to try it. I messaged the spell caster, and he assured me there was no problem and that everything will be okay before three days. He cast the spell and surprisingly on the second day, my wife called me. I was so surprised, I answered the call and all she said was that she was so sorry for everything that had happened she wanted me to return to her. She also said she loved me so much. I was so happy and went to her that was how we started living together happily again. The spell casters email is :dr.okisinsolutiontemple@gmail.com , or whatsapp/call_ +2348109374702 You can email him if you need his assistance in your relationship or any Other Case.1) Love Spells......2 Divorce Spells.....3 Marriage Spells......4 Binding Spell....5 Breakup Spell......6 Death spell.......7 win a court case spellContact this great man if you are having any problem for a lasting solutionthrough his whatsapp number +2348109374702 

    ReplyDelete
  13. Hello viewers, I'm here to shear my testimony on how Dr.Azu cured my herpes virus/hpv with his herbal medicine,,.I do not have much to say but with all my life i will for ever be grateful to him and God Almighty for using Dr.Azu to reach me when i thought it was all over, today i am happy with my life again after the medical doctor have confirmed my HERPES SIMPLEX VIRUS / HPV of 3 years is gone,i have never in my life believed that HERPES SIMPLEX VIRUS could be cured by herbal medicine. so i want to use this means to reach other persons who have this disease by testifying the power of  Dr.Azu that all hope is not lost yet, try and contact him by any means for any kind of disease. Thanks once again Dr.Azu for your marvelous work may God continue to bless you. You can also reach him today via email: dr.azuherbalhome@gmail.com or +2347087313747.     .

    ReplyDelete
  14. i am here to testify to the world about the goodness of david muhammed
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    he help with the herbal cure too, i was so happy that there is cure to
    this herpes1&2 i requested for the product in the next 4days the
    herbal was in my place in USA, i took it according to his instruction
    after everything and i went to hospital to do checkup and the result
    was negative and i was very happy about it,i email him again and thank
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    here to tell the world how david muhammed save my life, he is a man
    with is own destination you can believe in him with your life and he
    will give you good result, he also carry out all kinds of sickness like


    Money spell
    Health portion spell
    Promotion in business
    Attraction spell
    Witch home
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    Spiritual healer spell
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    Lottery spell
    Pregnancy spell
    Promotion spell
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    Get married spell
    Soulmate spell
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    HIV/aids
    Get pregnant
    Cure any kind in body disease
    E.T.C
    contact him via his email
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    ReplyDelete
  15. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

    This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  

    ReplyDelete
  16. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

    This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  

    ReplyDelete
  17. HOW I GOT MY HUSBAND BACK WITH THE HELP OF PRIEST WISDOM CONTACT ON WHATS_APP NUMBER +2348124644470

    This is my testimony about the good work of priest wisdom who help me.... I'm Ann Earnis from north Carolina USA. And am sorry for putting this on net but i will have to, by this world best spell caster that brought back my husband who left me out for past 3 years, i eventually me t this man on a blog site posting by one of is client for help, i explained everything to him and he told me about a spell caster that he had heard about and he gave me an email address to write to the spell caster to tell him my problems. In just 1 days, my husband was back to me. I just want to say thank you to this truthful and sincere spell caster, sir all you told me have come to pass and thank you sir. Please i want to tell everyone who is looking for any solution to their problem, i advice you to kindly consult this spell caster, he is real,he is powerful and whatever the spell caster tell is what will happen, because all what the spell caster told me came to pass. You can kindly contact him on: his email address is supernaturalspell1@gmail.com or directly on whats-app +2348124644470  or   https://supernaturalspell21.blogspot.com/  

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  18. LOVE SPELLS THAT WORKS, I completely trusted Dr Nana totally from the time I spoke with him during the period my husband Left me after Five years of our marriage, He started the spell work on my husband, and gave me so much assurance and guaranteed me that he was going to bring my husband back to my feet in just 11 hours of the spell casting. I was so confident in his work and just as he said in the beginning, my husband is finally back to me again, yes he is back with all his hearts, Love, care, emotions and flowers and things are better now. I would have no hesitation to recommend this powerful spell caster to anybody who is in need of help.. Email: nanakwakuspiritualist@gmail.com Or Call/WhatsApp him on
    +2349029905501. You Can also visit Website https://lovespellsite.blogspot.com/

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  19. I’m so happy to testify of the good work of Dr. patrick I Suffer from Herpes virus since 2007 and i had frequent symptoms in my private area, after some time it will go away after using acyclovir drugs, then come back after some months. it was disheartening since i have been diagnosed, but after finding Dr. patrick and his reviews i was convinced that he will definitely cure me and so i contacted and he told me how to get his medicine and using it for just 14 days and i will go and check up and first i said how can that be possible but i used his herbal medicine after making purchase and truly i used it and went for the test again, and my result came back negative. so i made it a task to share this good testimony in the internet so that those sick can benefit and get cured. What app or call:+2348055367947  Email:dr. patrickherbalhome@gmail.com      

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